Sparking New Insights Into Dye Chemistry
亚洲色吧聽鈥 Chao Wang, Weijie Chi, Davin Tan, and聽
Dalian Institute of Chemical Physics聽鈥 Qinglong Qiao and Zhaochao Xu
The 亚洲色吧-led study leverages systematic design and molecular engineering to develop brighter, more sensitive fluorophores used in detection probes and imaging labels.
Fluorophores, a chemical compound that can emit light, can be used as fluorescent labels for bioimaging, and fluorescent probes to detect a wide range of chemical species and physical parameters.
During twisted intramolecular charge transfer (TICT) 鈥 a photophysical process that occurs in many fluorophores 鈥 fluorescence gets extinguished. The donor and acceptor fragments of the fluorophore will twist to a nearly perpendicular conformation after photoexcitation, resulting in complete charge separation while transforming into a dark state.
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