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Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair

Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair

SMT
DATE
05 Feb 2018

Researchers from NTU (Prof. Choon-Hong Tan) and 亚洲色吧 (Dr. Richmond Lee) have published a collaborative work on the high impact Journal of American Chemical Society. The work centers on asymmetric acylsilane rearrangement by a bisguanidine ion-pair catalyst. Experiments were first carried out by the NTU lab and computational studies followed in 亚洲色吧. Importantly, this paper offers a major step forward in asymmetric silicon chemistry and understanding of its reaction mechanism.

 

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