亚洲色吧

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SUBBURAJ Karupppasamy

Adjunct Assistant Professor
EMAIL
subburaj
sutd.edu.sg
CONTACT
+65 6499 4897

Biography

Subburaj (Subbu) is an Assistant Professor in the Pillar of Engineering Product Development (EPD) at 亚洲色吧, where he leads Healthcare Engineering and Design Specialisation Track and the Lab. He leads an inter-disciplinary research team with the goal of designing and developing medical devices, assistive technologies, image-based quantitative biomarkers, and computing tools (FEA / ML / AI) for diagnosing, monitoring, treating, and potentially preventing musculoskeletal disorders and disabilities (Osteoarthritis/ Osteoporosis / Scoliosis) by understanding bio-mechanical implications of these diseases and disabilities.

His research interest is on design innovation in medical devices, technologies, and methods for successful and active aging. More specifically on (1) biomechanical understanding of aging and its impact on the prevention, progression, and prognosis of illnesses, injuries, and associated disabilities; (2) developing effective early assessment and continuous monitoring systems, methods, devices, and tools to maintain health, well-being, and function and reduce the burden of age-related musculoskeletal fragility.

He collaborates with physicians and clinical researchers from Tan Tock Seng Hospital (TTSH), Technical University of Munich (TUM), Singapore General Hospital (SGH), and Changi General Hospital (CGH) to combine research and technical expertise to address real-life clinical problems affecting Asia-Pacific and the World.

Before joning 亚洲色吧, he did his postdoctoral work in Musculoskeletal Quantitative Imaging Research (MQIR) laboratory at University of California San Francisco (UCSF).  At UCSF, he worked with a spectrum of clinicians (from radiology, orthopaedic surgeons, sports medicine, and physiotherapy/rehabilitation science) on characterizing magnetic resonance image (MRI) based bio-markers to understand the physiological and biochemical response of knee joint cartilage to physical exercise and acute loading. He has also developed and validated 3D modelling and quantification methods to study joint (hip/knee) loading pattern and contact kinematics in young healthy adults and patients with osteoarthritis.
Education
  • Postdoc (’10-’14), University of California San Francisco (UCSF)
  • PhD (’05-’09), Indian Institute of Technology Bombay (IIT Bombay)
Research & Teaching Interests
  • Education  : Design-based Learning, Design Education, Experiential learning
  • Product       :Assistive Devices, Prosthetics, Surgical Tools, Health Monitoring
  • Tools             :Medical Imaging and Analysis, Computational Modelling and Simulation, Applied ML/AI tools
  • Scienc         :Design for Health, Quantitative Biomechanics, Bone and Joint Health
  • Diseases      :Age-related Fragility, Musculoskeletal Disabilities, Osteoarthritis, Osteoporosis
Selected Research Publications
  • T. Binedell T,K. Subburaj*, Y. Wong, LT Blessing, 鈥溾JMIR Rehabil Assist Technol. (2020), 7 (2), e23827.
  • T. Binedell, E. Meng,K. Subburaj*, 鈥,鈥Prosthet. Orthot. International, (2020),in press. PMID: 32842869
  • N.M. Rayudu, K. Subburaj*, K. Mei, M. Dieckmeyer, J.S. Kirschke, P.B. Noel, T. Baum, 鈥?鈥,Frontiers in Endocrinology, (2020), 11: 442.
  • N.M. Rayudu, D.P. Anitha, K. Mei, F. Zoffl, F.K. Kopp, N. Sollmann, M.T. L枚ffler, J.S. Kirschke, P.B. Noel,K. Subburaj*, T. Baum, 鈥,鈥Archives of Osteoporosis, (2020), 15(1): 17.
  • D. Anitha, T. Baum, J.S. Kirschke,K. Subburaj*,,鈥The Spine Journal, (2020), 20(4): 665-671.
  • S 膯ukovi膰, W Taylor, V Lukovi膰, I Ghionea, K Baizid, J Iqbal, K. Subburaj, 鈥,鈥 Computer-Aided Design & Applications, (2020), 17 (6), 1313-1325
  • D. Shriram, G. Yamako, E. Chosa,K. Subburaj*,,鈥IEEE Access,, (2019), 7: 140084 鈥 140101.
  • E. Burian,K. Subburaj,M. R. K. Mookiah, A. Rohrmeier, D. M. Hedderich, M. Dieckmeyer, M. N. Diefenbach, S. Ruschke, E. J. Rummeny, C. Zimmer, J. S. Kirschke, D. C. Karampinos, T. Baum, 鈥,鈥Osteoporosis International,, (2019), 30(6):1265-1274.
  • D. Shriram, G. Yamako, E. Chosa, YHD LeeK. Subburaj*, 鈥,鈥Journal of Orthopaedic Surgery and Research,, (2019), 14: 44.
  • D. Anitha,K. Subburaj*, F.K. Kopp, K. Mei, P. Foehr, R. Burgkart, N. Sollmann, C. Maegerlein, J.S. Kirschke, P.B. Noel, T. Baum, 鈥,鈥Journal of Computer Assisted Tomography, (2019), 43(1):61-65.
  • D. Anitha, K. Mei, M. Dieckmeyer, F.K. Kopp, N. Sollmann, C. Zimmer, J.S. Kirschke, P.B. Noel, T. Baum,K. Subburaj*, 鈥,鈥Clinical Neuroradiology, (2019),29(4):645-651.
  • M.R.K. Mookiah, A. Rohrmeier, M. Dieckmeyer, K. Mei, F.K. Kopp, P.B. Noel, J.S. Kirschke, T. Baum,K. Subburaj, 鈥,鈥Osteoporosis International, 29 (4) (2018), 825-835.
  • V. Srinivasan, B. Song, J. Luo,K. Subburaj, R.E. Mohan, L. Blessing, K.L. Wood, 鈥,鈥ASME Journal of Mechanical Design, 140(7), (2018), 071101.
  • M.R.K. Mookiah,K. Subburaj, K. Mei, F.K. Kopp, J. Kaesmacher, P.M. Jungmann, P. Foehr, P.B. Noel, J.S. Kirschke, T. Baum, 鈥,鈥Journal of Computer Assisted Tomography, 42(3) (2018), 441-447 .
  • M.R.K. Mookiah, T. Baum, K. Mei, F. Kopp, G. Kaissis, P. Foehr, P.B. Noel, J.S. Kirschke,K. Subburaj, 鈥,鈥Journal of Bone and Mineral Metabolism, 36 (3) (2018), 323-335
  • D. Shriram, G.P. Kumar, F. Cui, Y.H.D. Lee,K. Subburaj, 鈥,Scientific Reports, 7, (2017), 6011
  • D. Anitha, T. Baum, J.S. Kirschke,K. Subburaj鈥淩isk of Vertebral Compression Fractures in Multiple Myeloma patients: A finite-element study,鈥Medicine, 96(2),(2017), e5825.
  • D Anitha,K. Subburaj, K. Mei, F.K. Kopp, P. Foehr, P.B. Noel, J.S. Kirschke, T. Baum, 鈥淓ffects of dose reduction on bone strength prediction using finite element analysis,鈥Scientific Reports, 6,(2016), 38441.
  • G. Mohan, S. Magnitsky, G. Melkus,K. Subburaj, G. Kazakia, A.J. Burghardt, A. Dang, N.E. Lane, S. Majumdar, 鈥淜artogenin treatment prevented joint degeneration in a rodent model of osteoarthritis: a pilot study,鈥Journal of Orthopaedic Research, 34 (10),(2016), 1780-1789.
  • D. Lansdown, M. Zaid, V. Pedoia,K. Subburaj,C.B. Ma, R.B. Souza, X. Li, 鈥淩eproducibility measurements of three methods for calculating in vivo MRI-based knee kinematics,鈥Journal of Magnetic Resonance Imaging, 42(2), (2015), 533-538.
  • C.R. Wyatt, D. Kumar,K. Subburaj, S. Lee, L. Nardo, D. Narayanan, D. Lansdown, T. Vail, T.M. Link, R.B. Souza, S. Majumdar, 鈥淐artilage T1蟻 and T2 Relaxation Times in Patients With Mild鈥恡o鈥怣oderate Radiographic Hip Osteoarthritis,Arthritis & Rheumatology, 67(6), (2015), 1548 鈥 1556.
  • D. Kumar, R.B. Souza,K. Subburaj,T.D. Macleod, J. Singh, N.E. Calixto, L. Nardo, T.M. Link, X. Li, N.E. Lane, S. Majumdar, 鈥淎re There Sex Differences in Knee Cartilage Composition and Walking Mechanics in Healthy and Osteoarthritis Populations?,鈥Clinical Orthopedic Related Research, 473 (8),(2015), 2548-2558.
  • K. Subburaj, R.B. Souza, B.T. Wyman, M.-P. Hellio Le Graverand, T.M. Link, X. Li, S. Majumdar, 鈥淐hanges in MR relaxation times of the meniscus with acute loading: an in vivo pilot study in knee osteoarthritis,鈥 Journal of Magnetic Resonance Imaging, 41(2),(2015), 536-543.
  • T.D. MacLeod, K. Subburaj, S.J. Wu, D. Kumar, C.R. Wyatt, R.B. Souza, 鈥淢agnetic resonance analysis of loaded meniscus kinematics: a novel technique comparing persons with and without radiographic knee osteoarthritis,鈥 Skeletal Radiology, 44(1), (2015), 125-35.
  • K. Subburaj, A. Valentinitsch, A.B. Dillon, G.B. Joseph, X. Li, T.M. Link, T.P. Vail, S. Majumdar, 鈥淩egional variations in MR relaxation of hip joint cartilage in subjects with and without femoralacetabular impingement,鈥 Magnetic Resonance Imaging, 31(7), (2013), 1129鈥1136.
  • D. Kumar,K. Subburaj, W. Lin, D.C. Karampinos, X. Li, R.B. Souza, T.M. Link, S. Majumdar, 鈥淨uadriceps and hamstrings morphology is related to walking mechanics and knee cartilage MR relaxation times in young adults,鈥Journal of Orthopaedic and Physical Therapy, 43(2), (2013) 881-890. 
  • K. Subburaj, D. Kumar, R.B Souza, H. Alizai, X. Li, T.M. Link, S. Majumdar, 鈥淭he Acute effect of running on knee articular cartilage and meniscus magnetic resonance relaxation times in young healthy adults,鈥 American Journal of Sports Medicine, 40(9), (2012), 2134鈥2141.
  • A. Kothari, B. Haughom,K. Subburaj, B. Feeley, X. Li, C.B. Ma, 鈥淓valuating rotational kinematics of the knee in ACL reconstructed patients using MRI,鈥The Knee, 19(5) (2012), 648鈥651.
  • K. Subburaj, R.B. Souza, C. Stehling, B.T. Wyman, M.-P. Hellio Le Graverand, T.M. Link, X. Li, S. Majumdar, 鈥淎ssociation of MR relaxation and cartilage deformation in knee osteoarthritis,鈥 Journal of Orthopaedic Research, 30(6) (2012), 919鈥926.
  • K. Subburaj, B. Ravi, M.G. Agarwal, “Computer-aided methods for assessing lower limb deformities in orthopaedic surgery planning,”Computerized Medical Imaging Graphics, 34(4) (2010) 277鈥288.
  • K. Subburaj, B. Ravi, M.G. Agarwal, “Automated identification of anatomical landmarks on 3D bone models reconstructed from CT data,”Comput. Medical Imaging Graphics, 33(5) (2009), 359鈥368.
  • K. Subburaj, C. Nair, S. Rajesh, S.M. Meshram, B. Ravi, 鈥淩apid development of auricular prosthesis using CAD and Rapid Prototyping (RP) technologies,鈥International J. Oral Maxillofacial Surgery, 36(10) (2007), 938鈥943.
Clinical Applications
  • Medical Devices Design
  • Rehabilitation / Assistive Devices
  • Orthopedic Biomechanics
  • Medical Imaging (MR / CT)
  • Modeling and Simulation
  • Osteoarthritis / Cartilage Tissue Damage
  • Osteoporosis / Bone Fracture
  • Scoliosis / Analysis / Implants
Opportunities

 

I am admitting PhD students in following areas:

  • Medical Image Analysis / Image Processing
  • Computational Geometry / Geometric Reasoning
  • Medical device Design /聽 Biomechanics
  • Finite Element Analysis / Modeling and Simulation
  • Medical Imaging (MRI / CT)
  • Machine Learning / AI Tools

Please contact (subburaj@sutd.edu.sg) with your CV and short statement on your research experience.